the inhibition effects of two species of astragalus extracts on mushroom
نویسندگان
چکیده
melanin pigment plays a critical role in camouflage and protection against harmful effects of solar radiation. melanogenesis is under complex regulatory control by multiple agents. tyrosinase is a multifunctional, which catalyzes the first two steps in mammalian melanogenesis. in this study, inhibitory effects of astragalus fasciculifolius and astragalus gypsicolus on diphenolase activity of mushroom tyrosinase were evaluated. .ethanol 80% extracts were prepared for screening tests. the ic 50 , k i , km and vm values of astragalus fasciculifolius and astragalus gypsicolus were measured then compared them. we found that both extracts show mixed type inhibition on mushroom tyrosinase when l-dopa was used as a substrate.
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عنوان ژورنال:
applied biotechnology reportsجلد ۱، شماره ۲، صفحات ۰-۰
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